5'-nucleotidase is a protein produced by the liver. 5'-NT test can be done to measure the amount of this protein in your blood.
5′ nucleotidase is used to investigate the origin of increased serum alkaline phosphatase. It is a liver-related enzyme used to work up the cholestatic/biliary obstruction. It parallels the increases of alkaline phosphatase and leucine aminopeptidase in hepatobiliary diseases but is not usually elevated in skeletal disorders such as Paget disease of bone. It is increased with metastatic neoplasia in the liver and in primary biliary cirrhosis, biliary obstruction from calculi and tumour.
The test is often performed for similar purposes as the alkaline phosphatase (ALP) and gamma-glutamyltransferase (GGT) tests.
Enzyme Cascade to Trinder Reaction
Random blood sample. No special preparation required.
Following are the clinical indications for performing the 5’-Nucleotidase Blood Test:
The laboratory test results are NOT to be interpreted as results of a "stand-alone" test. The test results have to be interpreted after correlating with suitable clinical findings and additional supplemental tests/information. Your healthcare providers will explain the meaning of your tests results, based on the overall clinical scenario.
Certain medications that you may be currently taking may influence the outcome of the test. Hence, it is important to inform your healthcare provider of the complete list of medications (including any herbal supplements) you are currently taking. This will help the healthcare provider interpret your test results more accurately and avoid unnecessary chances of a misdiagnosis.
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